67271-25-4Relevant academic research and scientific papers
The acid-promoted reactions of phenyliodonium ylides with substituted anilines and their applications to the synthesis of indoles
Wang, Xianpei,Han, Bing,Wang, Junyan,Yu, Wei
supporting information; experimental part, p. 3865 - 3867 (2010/09/17)
The N-substituted anilines 1 react readily with phenyliodonium ylides 2 derived from 1,3-dicarbonyl compounds in the presence of a catalytic amount of BF3·Et2O, forming the C-N coupling products 3, which are precursors for the synthesis of indoles. On the basis of this result, the direct synthesis of indoles from 1 and 2 under thermal conditions and photochemical conditions was explored. The transformations could be achieved in a one-pot way under thermal conditions or in a tandem manner under photochemical conditions.
