67273-00-1Relevant academic research and scientific papers
Palladium-Catalyzed Aminocarbonylation of Aryl Halides with 2,4,6-Trichloro-1,3,5-triazine/Formamide Mixed Reagent
Iranpoor, Nasser,Panahi, Farhad,Roozbin, Fatemeh,Erfan, Soodabeh,Rahimi, Sajjad
, p. 1781 - 1787 (2016)
In this work, the mixture of formamide and 2,4,6-trichloro-1,3,5-triazine (cyanuric chloride or TCT) is introduced as a new amidating agent in Pd-catalyzed aminocarbonylation of aryl halides. In the presence of a catalytic amount of palladium and TCT/formamide reagent, a range of aryl halides (X = Cl, Br, I) were converted into amides efficiently in N,N-dimethylformamide at 120 °C. The 2,4,6-trichloro-1,3,5-triazine/formamide mixed reagent was found to be an efficient amidating agent in Pd-catalyzed aminocarbonylation of aryl halides. In the presence of this reagent and a catalytic amount of Pd, a range of amides were synthesized by using aryl halides.
WCl6/DMF as a new reagent system for the phosphine-free Pd(0)-catalyzed aminocarbonylation of aryl halides
Iranpoor, Nasser,Firouzabadi, Habib,Rizi, Zeinab Tavangar,Erfan, Soodabeh
, p. 43178 - 43182 (2015/02/19)
WCl6 in dimethyl formamide (DMF) is introduced as a new reagent system for aminocarbonylation of aryl halides in the presence of PdCl2 as pre-catalyst without any phosphorous ligand. Aryl iodides, bromides as well as chlorides were efficiently converted to their corresponding N,N-dimethyl amides in good to high yields. In this protocol, WCl6/DMF is responsible for the generation of both Pd(0) catalyst as well as the formation of a Vilsmeier imminium type intermediate.
Silicadiphenyl phosphinite (SDPP)/Pd(0) nanocatalyst for efficient aminocarbonylation of aryl halides with POCl3 and DMF
Iranpoor, Nasser,Firouzabadi, Habib,Motevalli, Somayeh
experimental part, p. 69 - 74 (2012/03/09)
Silicadiphenyl phosphinite (SDPP) as a new phosphorylated silica and catalytic amounts of Pd(II) generates nano SDPP/Pd(0) catalyst for the efficient aminocarbonylation of aryl halides in the presence of POCl3 and N,N-dimethylformamide (DMF). Amides are obtained in high yields from aryl iodides and also activated aryl bromides, chlorides.
