5326-38-5

Basic information

• Product Name: 2-IODO-5-NITROTOLUENE
• Synonyms: 2-IODO-5-NITROTOLUENE;2-IODO-5-NITROTOLUENE 98+%;1-Iodo-2-methyl-4-nitrobenzene;2-Iodo-5-nitrotoluene 97%
• CAS NO: 5326-38-5
• Molecular Formula: C₇H₆INO₂
• Molecular Weight: 263.03
• EINECS: 226-204-1
• Product Categories: Nitro Compounds;Nitrogen Compounds;Organic Building Blocks
• Mol File: 5326-38-5.mol
• Article Data: 9

Chemical Properties

• Melting Point: 103-107 °C(lit.)
• Boiling Point: 309.2°Cat760mmHg
• Flash Point: 140.8°C
• Appearance: /
• Density: 1.883g/cm³
• Vapor Pressure: 2.23E-11mmHg at 25°C
• Refractive Index: 1.665
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Sensitive: Light Sensitive
• BRN: 2438587
• CAS DataBase Reference: 2-IODO-5-NITROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IODO-5-NITROTOLUENE(5326-38-5)
• EPA Substance Registry System: 2-IODO-5-NITROTOLUENE(5326-38-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 5326-38-5(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C16H15N3O/c1-10(2)17-16(20)11-6-5-9-14-15(11)19-13-8-4-3-7-12(13)18-14/h3-10H,1-2H3,(H,17,20)

Upstream product

• 615-37-2 ortho-methylphenyl iodide 
• 99-52-5 2-methyl-4-nitro-benzenamine 
• 7664-93-9 sulfuric acid 

Downstream Products

• 4949-69-3 4-iodo-3-methylaniline 
• 855931-99-6 acetic acid-[4-(2-methyl-4-nitro-phenylsulfanyl)-anilide] 
• 141397-32-2 1-(4-nitro-2-methylphenyl)-8-(2-methylphenyl)naphthalene 
• 1960-52-7 2-methyl-4-nitro-1-(trifluoromethyl)benzene 
• 183946-06-7 1-pentafluoroethyl-2-methyl-4-nitro-benzene 
• 108-44-1 1-amino-3-methylbenzene 
• 869896-51-5 methyl 2-{[2-(2-methyl-4-nitrophenyl)-2-propenyl](phenylsulfonyl)amino}-4-pentenoate 
• 883715-41-1 5,5-dimethyl-2-(2-methyl-4-nitro-phenyl)-[1,3,2]dioxaborinane 
• 673456-19-4 2-(2-bromomethyl-4-nitro-phenyl)-5,5-dimethyl-[1,3,2]dioxaborinane 
• 106877-31-0 3-methyl-4-trifluoromethylphenylamine 
• 183946-08-9 1-pentafluoroethyl-2-methyl-4-amino-benzene 
• 179637-55-9 2-Cyano-N-(3-methyl-4-trifluoromethyl-phenyl)-acetamide 
• 1025944-91-5 2-Cyano-N-(3-methyl-4-pentafluoroethyl-phenyl)-acetamide 
• 147076-36-6 (1-(3-methyl-4-trifluoromethylphenyl-carbomyl)-2-cyclopropyl-2-oxo-propionitrile) 

Relevant articles and documents

Aryl or N-heteroaryl Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands

The invention relates to aryl or N-heteroaryl substituted methanesulfonamide derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

Amine Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands

The invention relates to amine substituted methanesulfonamide derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

NON-SYSTEMIC TGR5 AGONISTS

Compounds of structure (I), or a stereoisomer, tautomer, pharmaceutically acceptable salt or prodrug thereof, wherein R1, R2, R3, R4, R8, R9, R10, R11, R12, A1, A2, X, Y and Z are as defined herein. Uses of such compounds as TGR5 antagonists and for treatment of various indications, including Type II diabetes meletus are also provided.