672963-92-7

Upstream product

• 55-21-0 benzamide 
• 26464-05-1 2-bromo-3-methyl-butyryl bromide 
• 672963-84-7 N-benzoyl-2-bromo-3-methylbutanamide 

Downstream Products

• 1353719-69-3 (S)-5-isopropyl-5-((R)-3-oxo-1-phenylbutyl)-2-phenyloxazol-4(5H)-one 
• 1353719-70-6 (S)-5-isopropyl-5-((R)-1-(3-methoxyphenyl)-3-oxobutyl)-2-phenyloxazol-4(5H)-one 
• 1353719-71-7 (S)-5-((R)-1-(4-chlorophenyl)-3-oxobutyl)-5-isopropyl-2-phenyloxazol-4(5H)-one 
• 1286783-53-6 methyl (Z)-3-[(R)-5H-5-(1-methylethyl)-4-oxo-2-phenyloxazol-5-yl]propenoate 
• 1286783-63-8 (R)-5H-5-(1-methylethyl)-5-[(Z)-3-oxo-3-(pyrrolidin-1-yl)propenyl]-2-phenyloxazol-4-one 

Relevant academic research and scientific papers

Non-hydrogen bond catalyst-mediated diastereoselective conjugate additions of 5: H -oxazol-4-ones to o -hydroxyphenyl-substituted p -quinone methides

An efficient DBU-catalyzed conjugate addition of 5H-oxazol-4-ones to o-hydroxyphenyl-substituted p-quinone methides has been developed, affording the valuable diarylmethanes in high yields with excellent diastereoselectivity. This strategy demonstrates a robust access to a wide range of diarylmethane derivatives possessing biologically significant o-hydroxyphenol and p-hydroxyphenol moieties under mild reaction conditions.

5H-Oxazol-4-ones as Building Blocks for Asymmetric Synthesis of α-Hydroxycarboxylic Acid Derivatives

5H-Alkyl-2-phenyl-oxazol-4-ones, a little-known heterocyclic ring system, are readily available via a microwave-assisted, sodium fluoride catalyst cyclization of mono-α-haloimides, which in turn are accessed by N-acylation of benzamides with α-bromo acid