67297-95-4

Usage

Uses

Used in Coordination Chemistry:
N,N',N''-Tri-2-pyridinyl-1,3,5-triazine-2,4,6-triamine is used as a chelating ligand for the formation of stable complexes with metal ions in coordination chemistry.
Used in Metal Complexation Studies:
N,N',N''-Tri-2-pyridinyl-1,3,5-triazine-2,4,6-triamine is used as a ligand in metal complexation studies to investigate the properties and applications of metal complexes.
Used in Catalysis:
N,N',N''-Tri-2-pyridinyl-1,3,5-triazine-2,4,6-triamine is used as a ligand in catalytic systems to enhance the activity and selectivity of catalysts.
Used in Molecular Recognition:
N,N',N''-Tri-2-pyridinyl-1,3,5-triazine-2,4,6-triamine is used in molecular recognition studies to develop receptors and sensors for the selective binding of target molecules.
Used in Biological Studies:
N,N',N''-Tri-2-pyridinyl-1,3,5-triazine-2,4,6-triamine is used in biological studies to explore its potential applications in drug design and development.
Used in Material Science:
N,N',N''-Tri-2-pyridinyl-1,3,5-triazine-2,4,6-triamine is used as a building block for the development of new materials and supramolecular assemblies in material science.

Upstream product

• 504-29-0 2-aminopyridine 
• 108-77-0 1,3,5-trichloro-2,4,6-triazine 

Relevant academic research and scientific papers

NNN-pincer-copper complex immobilized on magnetic nanoparticles as a powerful hybrid catalyst for aerobic oxidative coupling and cycloaddition reactions in water

A simple and reliable methodology is described for preparing the first heterogeneous NNN-pincer-copper hybrid catalyst with a high control over surface composition. The strategy relies on the covalently bonding of 2-aminopyridine to cyanuric chloride-functionalized magnetic nanoparticles followed by complexation with CuI. These claims are confirmed by different characterization methods such as SEM, TEM, FT-IR, TGA, ICP, XRD, and elemental analysis. The finely engineered supported catalyst is employed in the aerobic oxidative coupling of terminal alkynes and click reaction using only 0.38 and 0.04 mol% catalyst, respectively. All reactions perform under solvent-free condition or green solvent H2O. Also, the catalyst is readily recovered and reused for up to 8 and 6 subsequent runs in click and homocoupling reactions without significant loss of activity or leaching.

A novel series of potent cytotoxic agents targeting G2/M phase of the cell cycle and demonstrating cell killing by apoptosis in human breast cancer cells

Breast cancer, a leading cause of mortality in women, warrants the development and biological evaluation of new anticancer agents. A novel series of thiopyridine triazine derivatives was synthesized and investigated in the human breast cancer cell line, MDA-MB-468. SM40, the most potent derivative, induced a G2/M arrest and apoptosis with a possible involvement of p53. The cytotoxicity of SM40 was also examined against the NCI 60 cell line panel and its potency was rationalized using molecular modeling. Results suggest that SM40 is a promising cytotoxic agent.