67299-59-6Relevant academic research and scientific papers
Dynamic Control of Chiral Space Through Local Symmetry Breaking in a Rotaxane Organocatalyst
Dommaschk, Marcel,Echavarren, Javier,Leigh, David A.,Marcos, Vanesa,Singleton, Thomas A.
supporting information, p. 14955 - 14958 (2019/11/05)
We report on a switchable rotaxane molecular shuttle that features a pseudo-meso 2,5-disubstituted pyrrolidine catalytic unit on the axle whose local symmetry is broken according to the position of a threaded benzylic amide macrocycle. The macrocycle can
PROCESS FOR PRODUCTION OF MONO-SUBSTITUTED ALKYLATED COMPOUND USING ALDIMINE OR DERIVATIVE THEREOF
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Page/Page column 112-114, (2008/06/13)
Disclosed is a process for producing an asymmetric mono-substituted alkylated compound of an α-amino acid which is represented by a specific formula by using an aldimine-type Schiff base. In the process, the alkylation of an aldimine-type Schiff base in a medium in the presence of an optically active quaternary ammonium salt phase transfer catalyst and an inorganic base is started, and subsequently the reaction is quenched at any time preceding the completion of the stoichimetrical reaction, thereby yielding a mono-substituted alkylated product having a high optical purity.
