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Tris(2-(1-methylimidazolyl)methanol), also known as TMIT, is a chelating agent commonly used in various applications, including the stabilization of metal ions in biological systems and as a component in certain buffer solutions. It is a white crystalline solid with the chemical formula C12H18N4O3. TMIT is known for its ability to form stable complexes with metal ions, which makes it useful in preventing metal-catalyzed oxidation and other unwanted reactions in biological samples. Its structure features three imidazole rings, which are effective at binding metal ions through their nitrogen atoms, and a central hydroxyl group that can participate in hydrogen bonding. tris<2-(1-methylimidazolyl)>methanol is particularly important in the field of biochemistry and molecular biology, where it helps maintain the integrity of proteins and other biomolecules during experiments and storage.

67319-02-2

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67319-02-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 67319-02-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,3,1 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 67319-02:
(7*6)+(6*7)+(5*3)+(4*1)+(3*9)+(2*0)+(1*2)=132
132 % 10 = 2
So 67319-02-2 is a valid CAS Registry Number.

67319-02-2Relevant academic research and scientific papers

Synthesis of Ketones and Methanols Containing Pyridinyl and N-Methylimidazolyl Groups

Canty, Allan J.,George, Edwin E.,Lee, Christopher V.

, p. 415 - 418 (2007/10/02)

N-Methylimidazolyllithium reacts with N-methylimidazole-2-carboxaldehyde to form bis(N-methylimidazol-2-yl)methanol, and with the esters ethyl N-methylimidazole-2-carboxylate and ethyl pyridine-2-carboxylate to give bis(N-methylimidazol-2-yl)methanone, (mim)2CO, and (N-methylimidazol-2-yl)(pyridin-2-yl)methanone, (Py)(mim)CO, respectively.The ketones react with N-methylimidazolyllithium to give tris(N-methylimidazol-2-yl)methanol, (mim)3COH, and bis(N-methylimidazol-2-yl)(pyridin-2-yl)methanol, (Py)(mim)2COH, respectively.

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