67319-05-5

Upstream product

• 20075-26-7 1-(methoxymethyl)imidazole 
• 882-33-7 diphenyldisulfane 

Downstream Products

• 132287-56-0 4-diphenylhydroxymethyl-1-methoxymethyl-2-phenylthioimidazole 
• 1094172-70-9 C₃₅H₃₅N₃O₈S₂ 
• 1094172-71-0 C₃₈H₄₂N₄O₈S₂ 
• 1094172-72-1 C₃₆H₄₀N₄O₇S₂ 
• 1094172-73-2 C₄₃H₄₆N₄O₉S₃ 
• 1094172-58-3 C₁₁H₁₃BN₂O₃S 
• 1333378-21-4 C₂₉H₂₇N₃O₄S₂ 
• 1333378-30-5 C₃₆H₃₉N₇O₆S₂ 
• 1333378-12-3 C₃₁H₃₁N₇O₄S₂ 
• 1333378-11-2 C₄₁H₃₅BrN₈O₆S₂ 
• 219817-91-1 methyl (2-(1-methoxymethyl)-2-(phenylthio)imidazol-5-yl)glyoxylate 
• 132287-57-1 4-diphenylhydroxymethyl-1-methoxymethyl-imidazole 
• 219817-92-2 3-<4-(1-(methoxymethyl)-1H-2-(phenylthio)imidazol-5-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl>indole 
• 153172-35-1 2-(phenylthio)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole 

Relevant academic research and scientific papers

Synthetic studies on dragmacidin D: Synthesis and assembly of three fragments towards an advanced intermediate

We report herein the approach to the key advanced intermediate in the synthesis of the bioactive marine natural product dragmacidin D. By employing a modular synthesis strategy of three fragments (5, 7, and 8), the advanced intermediate 3 has been successfully synthesized in 2.5% yield over 15 steps by starting from nitrotoluene 20. The synthesis also involves sequential cross-coupling reactions, namely Sonogashira and Suzuki-Miyaura reactions, so that various analogues can be efficiently synthesized, which will allow the study of structure-activity relationships of dragmacidin D.

Extending pummerer reaction chemistry: Studies in the palau'amine synthesis area

Exploratory oxidative cyclization studies on cyclopentanelated and cyclohexenelated oroidin derivatives utilized Pummerer chemistry to generate pentacyclic structures related to the palau'amine family of sponge metabolites. Stereochemical issues were para