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3-(4-hydroxyphenoxy)benzyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate is a complex organic compound with the chemical formula C22H21Cl2O4. It is a derivative of cyclopropanecarboxylic acid, featuring a benzyl group attached to a hydroxyphenoxy moiety and a dichloroethenyl group. 3-(4-hydroxyphenoxy)benzyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate is known for its potent insecticidal properties, particularly against mites and ticks. It functions by disrupting the nervous system of the target pests, leading to paralysis and death. Due to its specific chemical structure, it is effective in controlling a range of agricultural and horticultural pests, making it a valuable tool in integrated pest management strategies.

67328-58-9

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67328-58-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 67328-58-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,3,2 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 67328-58:
(7*6)+(6*7)+(5*3)+(4*2)+(3*8)+(2*5)+(1*8)=149
149 % 10 = 9
So 67328-58-9 is a valid CAS Registry Number.

67328-58-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name [3-(4-hydroxyphenoxy)phenyl]methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate

1.2 Other means of identification

Product number -
Other names 4-OH-c,t-permethrin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:67328-58-9 SDS

67328-58-9Downstream Products

67328-58-9Relevant academic research and scientific papers

Stereoselective biotransformation of permethrin to estrogenic metabolites in fish

Nillos, Mae Grace,Chajkowski, Sarah,Rimoldi, John M.,Gan, Jay,Lavado, Ramon,Schlenk, Daniel

, p. 1568 - 1575 (2010)

This study investigated the stereoselective biotransformation and resulting estrogenic activity of the pyrethroid insecticide, permethrin (PM). Results of both in vivo (male Japanese medaka, vitellogenin (VTG) protein in plasma) and in vitro (primary rainbow trout hepatocyte VTG-mRNA expression) assays indicated stereoselective estrogenic activity of PM. 1S-cis-PM was observed to have significantly higher activity (P ≤ 0.05) than the 1R-cis enantiomer in both in vivo and in vitro evaluations. All enantiomers of PM were oxidized to a 4′-hydoxy PM (4OH PM) metabolite and underwent esterase cleavage to 3-phenoxybenzyl alcohol (3-PBOH) and 3-(4′-hydroxyphenoxy)-benzyl alcohol) (3,4′-PBOH). Racemic 4OH PM as well as 3-PBOH, and 3,4′-PBOH possessed significant (P ≤ 0.05) estrogenicity. 1S-trans-PM underwent esterase cleavage more extensively than the corresponding 1R-trans-PM. Inhibition studies with ketoconazole confirmed cytochrome P450-catalyzed hydroxylation as well as esterase cleavage of PM for all stereoisomers. These studies indicated stereoselectivity in the estrogenic activity of PM resulting from stereoselective biotransformation of the parent compound to more estrogenic metabolites.

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