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Uridine 5'-diphospho-2-fluoro-2-deoxy-α-D-mannopyranoside, also known as UDP-2-fluoro-2-deoxy-α-D-mannose, is a chemical compound that plays a crucial role in the biosynthesis of certain glycoconjugates, which are molecules containing a carbohydrate component. uridine 5'-diphospho-2-fluoro-2-deoxy-α-D-mannopyranoside is a derivative of uridine diphosphate (UDP) sugar, where the sugar component is 2-fluoro-2-deoxy-α-D-mannose, a fluorinated and deoxygenated version of the natural sugar mannose. The presence of fluorine in the molecule can enhance its stability and reactivity, making it a valuable tool in chemical and biological research, particularly in the study of enzyme mechanisms and the development of new drugs. The compound is synthesized through a series of chemical reactions and is used as a substrate in enzymatic reactions, providing insights into the role of sugar molecules in various biological processes.

67341-44-0

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67341-44-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 67341-44-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,3,4 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 67341-44:
(7*6)+(6*7)+(5*3)+(4*4)+(3*1)+(2*4)+(1*4)=130
130 % 10 = 0
So 67341-44-0 is a valid CAS Registry Number.

67341-44-0Downstream Products

67341-44-0Relevant academic research and scientific papers

Efficient one-pot multienzyme synthesis of UDP-sugars using a promiscuous UDP-sugar pyrophosphorylase from Bifidobacterium longum (BLUSP)

Muthana, Musleh M.,Qu, Jingyao,Li, Yanhong,Zhang, Lei,Yu, Hai,Ding, Li,Malekan, Hamed,Chen, Xi

, p. 2728 - 2730 (2012)

A promiscuous UDP-sugar pyrophosphorylase (BLUSP) was cloned from Bifidobacterium longum strain ATCC55813 and used efficiently with a Pasteurella multocida inorganic pyrophosphatase (PmPpA) with or without a monosaccharide 1-kinase for one-pot multienzyme synthesis of UDP-galactose, UDP-glucose, UDP-mannose, and their derivatives. Further chemical diversification of a UDP-mannose derivative resulted in the formation of UDP-N-acetylmannosamine. The Royal Society of Chemistry 2012.

CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS

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Paragraph 0323; 0324; 0331, (2014/09/03)

The present invention provides a one-pot multi-enzyme method for preparing UDP-sugars from simple sugar starting materials. The invention also provides a one-pot multi-enzyme method for preparing oligosaccharides from simple sugar starting materials.

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