67341-53-1

Basic information

• Product Name: 2(1H)-Pyrazinone, 6-methyl-3-phenyl-
• CAS NO: 67341-53-1
• Molecular Formula: C11H10N2O
• Molecular Weight: 186.213
• Mol File: 67341-53-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2(1H)-Pyrazinone, 6-methyl-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pyrazinone, 6-methyl-3-phenyl-(67341-53-1)
• EPA Substance Registry System: 2(1H)-Pyrazinone, 6-methyl-3-phenyl-(67341-53-1)

Safety Data

• Hazardous Substances Data: 67341-53-1(Hazardous Substances Data)

Upstream product

• 69-53-4 ampicillin 
• 50-00-0 formaldehyd 
• 69-53-4 ampicillin 
• 15686-71-2 cefalexin 
• 20721-18-0 6-methylpyrazin-2-one 
• 100-34-5 benzene diazonium chloride 

Downstream Products

• 99851-79-3 5-bromo-6-methyl-3-phenyl-1H-pyrazin-2-one 

Relevant articles and documents

2-Hydroxy-3-aryl-6-methylpyrazines; fluorophores formed from the reaction of formaldehyde with cyclic enamine degradation products common to β-lactam antibiotics with aryl glycine side chains

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Isolation and identification of the fluorescent degradation product of some β-lactam antibiotics

A fluorescent degradation product of cephalexin, recently employed in the determination of this antibiotic in aqueous solution and human plasma, has been isolated and identified as 2-hydroxy-3-phenyl-6-methylpyrazine. Spectroscopically and chromatographically the product is indistinguishable from that obtained by the same method from a series of other cephalosporins and penicillins bearing an α-amino group on the side-chain, and from the pyrazine structure produced by synthesis. Two reported methods for the fluorimetric determination of ampicillin have also been found to yield the same degradation product and not the suggested diketopiperazine structure.