6736-94-3Relevant academic research and scientific papers
Novel quercetin glucosides from Helminthostachys zeylanica root and acceleratory activity of melanin biosynthesis
Yamauchi, Kosei,Mitsunaga, Tohru,Batubara, Irmanida
, p. 369 - 374 (2013)
Two novel quercetin glucosides, namely 4′-O-β-d-glucopyranosyl- quercetin-3-O-β-d-glucopyranosyl-(1→4)-β-d-glucopyranoside (compound 1) and 4′-O-β-d-glucopyranosyl-(1→2)-β-d- glucopyranosyl-quercetin-3-O-β-d-glucopyranosyl-(1→4) -β-d-glucopyranoside (compound 2), were isolated from Helminthostachys zeylanica root 50 % EtOH extract. Structural analysis of isolated compounds was achieved mainly by 600 MHz and 800 MHz NMR, UPLC-TOFMS and GC-MS. Of the two quercetin glucosides, compound 1 showed a high melanogenic acceleratory effect, 2.7 times higher than control, at 10 μM concentration in murine B16 melanoma cells, with no cytotoxic effect.
