67382-14-3Relevant academic research and scientific papers
TRANSCRIPTION FACTOR BRN2 INHIBITORY COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE
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, (2020/05/15)
The invention provides a variety of compounds having the structure of Formula I and uses of such compounds for treatment of various indications, including cancer as well as methods of treatment involving such compounds are also provided. The uses of the compounds may specifically include: bladder cancer, cholangiocarcinoma; colorectal cancer; diffuse large B-cell lymphoma (DLBC); liver cancer; ovarian cancer; thymoma; thyroid cancer; clear cell renal cell carcinoma (CCRCC); chromophobe renal cell carcinoma (ChRCC); prostate cancer; breast cancer; uterine cancer; pancreatic cancer; cervical cancer; uveal melanoma; acute myeloid leukemia (AML); head and neck cancer; small cell lung cancer (SCLC); lung adenocarcinoma sarcoma; mesothelioma; adenoid cystic carcinoma (ACC), sarcoma; testicular germ cell cancer; uterine cancer; pheochromocytoma and paraganglioma (PCPG); melanoma; glioma; glioblastoma multiforme; T-cell Acute Lymphoblastic Leukemia; T-cell Lympohoma, medulloblastoma; and neuroblastoma.
Chemistry of Thiazole, I. Synthesis and Properties of 2,3,5,6-Tetrahydro-6-(3-methyl-benzofuran-2-yl)imidazothiazole
Nielek, Stefan,Lesiak, Tadeusz
, p. 1247 - 1251 (2007/10/02)
Die Titelverbindung 13 wird auf zwei Wegen ausgehend von 2-Hydroxyacetophenon (1) ueber das Benzofuran-Derivat 7 und die Thiazolidine 9 bzw. 10 erhalten.
