67405-29-2Relevant academic research and scientific papers
Synthesis, stereochemistry, antimicrobial evaluation and QSAR studies of 2,6-diaryltetrahydropyran-4-one thiosemicarbazones
Umamatheswari,Balaji,Ramanathan,Kabilan
supporting information; experimental part, p. 1415 - 1424 (2011/04/23)
A series of 2,6-diaryltetrahydropyran-4-one thiosemicarbazones (11-27) were synthesized and characterized for evaluation of potential antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Bacillu
Synthesis, characterisation and antimicrobial activities of novel 7,9-diphenyl-1,2,4-triaza-8-oxa-spiro[4.5]-decan-3-thiones
Kabilan, Senthamaraikannan,Umamatheswari, Seeman
scheme or table, p. 542 - 548 (2012/04/17)
Some new 7,9-diaryl-1,2,4-triaza-8-oxa-spiro [4.5]-decan-3-thiones has been synthesised and their antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi, and antifungal activity against Candida albicans, Rhizopus sp., Aspergillus flavus and Aspergillus niger were examined. Compounds 14 and 15 against E. coli and S. typhi showed marked antibacterial activity. Similarly, compounds 13 and 15 against Rhizopus sp. and 13 and 14 against A. flavus exerted significant antifungal activities. Springer Science+Business Media, LLC 2011.
Synthesis, spectral, crystal and antimicrobial studies of biologically potent oxime ethers of nitrogen, oxygen and sulfur heterocycles
Parthiban, Paramasivam,Aridoss, Gopalakrishnan,Rathika, Paramasivam,Ramkumar, Venkatachalam,Kabilan, Senthamaraikannan
supporting information; experimental part, p. 2981 - 2985 (2010/03/03)
Three series of oxime ethers viz, 2,6-diarylpiperidin-4-one O-benzyloximes 5a-o, 2,6-diaryltetrahydropyran-4-one O-benzyloximes 7a-e and 2,6-diaryltetrahydrothiopyran-4-one O-benzyloximes 11a-b and 12a-c were synthesized and stereochemistry is established by their spectral and single crystal analysis. A SAR study has been carried out for the above oxime ethers against a panel of antibacterial (Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi and Escherichia coli) and antifungal agents (Candida albicans, Candida-51, Rhizopus sp., Aspergillus niger, Aspergillus flavus and Cryptococcus neoformans), respectively, using Ciprofloxacin and Amphotericin B as standards. Most of the chloro/methyl/methoxy substituted compounds exerted moderate to good activity against all the tested organisms; moreover, some compounds (5i, 5l, 5n, 5o, 7c2, 7d1, 7d2, 7e, 11b and 12c) exhibited promising activity than standard drugs.
Spectral characterization and crystal structure of 5-spiro-(3-methyl-2,6-diphenyltetrahydropyran-4-yl)-4,5-dihydro-[1,3,4]thiadiazole
Umamatheswari,Kabilan
scheme or table, p. 142 - 149 (2010/04/01)
The synthesis of new 1,3,4-thiadiazoline derived from 3-methyl-2,6-diphenyltetrahydropyran-4-one, via the corresponding thiosemicarbazone, is described. The synthesis, spectral characterization and crystal structure of 5-spiro-1,3,4-thiadiazoline of 2,6-d
Dissociation Constants of Cyanohydrins of Some Tetrahydropyran-4-ones
Baliah, V.,Mangalam, G.
, p. 947 - 948 (2007/10/02)
The dissociation constants of cyanohydrins of some substituted tetrahydropyran-4-ones have been determined at 30 deg in 80percent dioxane-water (v/v).The results substantiate the steric environment of the carbonyl group in these ketones.
