6742-26-3

Basic information

• Product Name: ethyl 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate
• Synonyms: ethyl 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate
• CAS NO: 6742-26-3
• Molecular Formula: C₁₃H₁₄O₃
• Molecular Weight: 218.25
• Mol File: 6742-26-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 33 °C
• Boiling Point: 333.8°C at 760 mmHg
• Flash Point: 146.7°C
• Appearance: /
• Density: 1.167g/cm³
• Vapor Pressure: 0.000133mmHg at 25°C
• Refractive Index: 1.541
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 10.69±0.20(Predicted)
• CAS DataBase Reference: ethyl 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate(6742-26-3)
• EPA Substance Registry System: ethyl 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate(6742-26-3)

Safety Data

• Hazardous Substances Data: 6742-26-3(Hazardous Substances Data)

Usage

General Description

Ethyl 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate is an organic compound with a complex chemical structure. It is classified as an ester, containing an ethyl group, a carboxylic acid group, and a naphthalene ring. The compound is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and functional groups make it a valuable precursor in organic chemistry, allowing for the creation of diverse molecules with different biological and chemical properties. Additionally, it can be used as a fragrance ingredient and flavoring agent in the food and beverage industry. However, it is important to handle and use this compound with care, as it may pose potential health and safety hazards if not properly managed.

InChI:InChI=1/C13H14O3/c1-2-16-13(15)11-8-7-9-5-3-4-6-10(9)12(11)14/h3-6,11H,2,7-8H2,1H3/t11-/m1/s1

Upstream product

• 1829-28-3 ethyl 2-iodobenzoate 

Downstream Products

• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 78140-78-0 ethyl 2-benzyl-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate 
• 1081-27-2 4-(2-carboxy-phenyl)-butyric acid 
• 53440-12-3 1,2,3,4-tetrahydro-2-naphthoic acid 
• 22440-38-6 3,4-dihydronaphthalene-2-carboxylic acid 
• 86-48-6 1-hydroxy-2-naphthoic acid 
• 21370-71-8 trans-1-decalone 
• 194540-36-8 benzyl 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate 
• 1276046-11-7 ethyl 2-(3-(ethoxycarbonyl)but-3-enyl)benzoate 
• 1276046-12-8 ethyl 4-(2-(4-methoxybenzylcarbamoyl)phenyl)-2-methylenebutanoate 
• 1617568-17-8 ethyl (R)-2-((R)-2-(methoxycarbonyl)-1-phenylallyl)-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate 

Relevant articles and documents

Construction of Polycyclic β-Ketoesters Using a Homoconjugate Addition/Decarboxylative Dieckmann Annulation Strategy

The construction of arene-fused cyclic β-ketoesters from 2-iodoaryl esters and 1,1-cyclopropane diesters is detailed. The synthetic method takes advantage of a CuI·SMe2-mediated homoconjugate addition followed by a decarboxylative Dieckmann cyclization to afford valuable polycyclic building blocks. Various iodoaryl esters and 1,1-cyclopropane diesters were evaluated, and the limitations of both reactions are discussed. Several mechanistic probes are detailed and synthetic applications are described.