674291-05-5Relevant academic research and scientific papers
Retro hydrazino-azapeptoids as peptidomimetics of proteasome inhibitors
Aubin, Sandrine,Martin, Bénédicte,Delcros, Jean-Guy,Arlot-Bonnemains, Yannick,Baudy-Floc'h, Michèle
, p. 330 - 334 (2007/10/03)
Several groups of proteasome inhibitors are widely used to study the role of the ubiquin proteasome pathway in various cellular processes or as anticancer drugs. Peptidomimetics have been developed to circumvent problems inherent in peptides such as poor
Hydrazino-aza and N-azapeptoids with therapeutic potential as anticancer agents
Bouget, Karine,Aubin, Sandrine,Delcros, Jean-Guy,Arlot-Bonnemains, Yannick,Baudy-Floc'h, Michele
, p. 4881 - 4889 (2007/10/03)
The ubiquitin-proteasome-mediated degradation pathway plays an important role in regulating protein turnover in eucaryotic cells and, consequently, regulates both cell proliferation and cell death. The proteasome influences many cellular regulatory signal
