67445-86-7

Basic information

• Product Name: 2-BroMo-N-[4-chloro-2-(4-hydroxybenzoyl)phenyl]acetaMide
• Synonyms: 2-BroMo-N-[4-chloro-2-(4-hydroxybenzoyl)phenyl]acetaMide
• CAS NO: 67445-86-7
• Molecular Formula: C₁₅H₁₁BrClNO₃
• Molecular Weight: 368.60974
• Mol File: 67445-86-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 201-203 °C(Solv: ethanol (64-17-5))
• Boiling Point: 615.9±55.0 °C(Predicted)
• Appearance: /
• Density: 1.644±0.06 g/cm3(Predicted)
• Solubility: DCM, Ethyl Acetate
• PKA: 7.58±0.15(Predicted)
• CAS DataBase Reference: 2-BroMo-N-[4-chloro-2-(4-hydroxybenzoyl)phenyl]acetaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BroMo-N-[4-chloro-2-(4-hydroxybenzoyl)phenyl]acetaMide(67445-86-7)
• EPA Substance Registry System: 2-BroMo-N-[4-chloro-2-(4-hydroxybenzoyl)phenyl]acetaMide(67445-86-7)

Safety Data

• Hazardous Substances Data: 67445-86-7(Hazardous Substances Data)

Usage

Uses

2-Bromo-N-[4-chloro-2-(4-hydroxybenzoyl)phenyl]acetamide is an intermediate in the preparation of Diazepam (D416855), an anxiolytic agent, muscle relaxant and anticonvulsant agent.

Upstream product

• 784-41-8 2-amino-5-chloro-4'-hydroxy-benzophenone 
• 598-21-0 2-Bromoacetyl bromide 

Downstream Products

• 17270-12-1 4'-hydroxy-N-desmethyldiazepam 

Relevant articles and documents

Immunoassay for N-desmethyldiazepam

Highly specific antibodies to N-desmethyldiazepam are obtained by using as an immunogen 4'-hydrazinocarbonylmethoxy-N-desmethyldiazepam coupled to an immunogenic carrier material such as bovine serum albumin. These antibodies can be employed in immunoassa

Benzodiazepine radioimmunoassay using I125-label

An improved radioimmunoassay for benzodiazepines such as diazepam, chlordiazepoxide, oxazepam, demoxepam and metabolites thereof is disclosed. Such immunoassay employs novel 125 I-labelled 4'-hydroxy derivatives of these compounds as tracer.