67451-42-7

Basic information

• Product Name: (2-FORMYL-1H-PYRROL-1-YL)ACETIC ACID
• Synonyms: (2-FORMYL-1H-PYRROL-1-YL)ACETIC ACID;2-(2-formyl-1-pyrrolyl)acetic acid;2-(2-formylpyrrol-1-yl)acetic acid;2-(2-methanoylpyrrol-1-yl)ethanoic acid
• CAS NO: 67451-42-7
• Molecular Formula: C₇H₇NO₃
• Molecular Weight: 153.13538
• Mol File: 67451-42-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 140-141 °C(Solv: water (7732-18-5))
• Boiling Point: 358.4±22.0 °C(Predicted)
• Appearance: /
• Density: 1.28±0.1 g/cm3(Predicted)
• PKA: 2.60±0.10(Predicted)
• CAS DataBase Reference: (2-FORMYL-1H-PYRROL-1-YL)ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2-FORMYL-1H-PYRROL-1-YL)ACETIC ACID(67451-42-7)
• EPA Substance Registry System: (2-FORMYL-1H-PYRROL-1-YL)ACETIC ACID(67451-42-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 67451-42-7(Hazardous Substances Data)

Usage

General Description

(2-Formyl-1H-pyrrol-1-yl)acetic acid is a chemical compound with the molecular formula C7H7NO3. It is a derivative of pyrrole and contains a formyl group and an acetic acid group. (2-FORMYL-1H-PYRROL-1-YL)ACETIC ACID is often used in research and pharmaceuticals due to its potential biological and medicinal properties. It may have applications in the development of drugs for various diseases and conditions. Additionally, it could be used as a building block for the synthesis of other organic compounds. Overall, (2-Formyl-1H-pyrrol-1-yl)acetic acid has potential as a valuable compound in the field of chemistry and medicine.

Upstream product

• 70582-73-9 ethyl 2-(2-formyl-1H-pyrrol-1-yl)acetate 
• 65057-97-8 tetrahydro-2,5-dimethoxy-2-furaldehyde dimethyl acetal 
• 56-40-6 glycine 
• 1003-29-8 2-pyrrole aldehyde 
• 79-08-3 bromoacetic acid 

Downstream Products

• 145041-27-6 (2-aminomethyl-1H-pyrrol-1-yl)acetic acid 

Relevant articles and documents

Semisynthetic cephalosporins. Synthesis and structure-activity relationships of 7-(1-pyrryl)- and 7-(1-indolyl)acetamidocephalosporin derivatives

A series of 1-pyrrole- and 1-indoleacetamido derivatives of 3-heteroaryl-substituted cephalosporins was prepared. The most active compound in the series was 7[[2-(1-pyrryl)acetyl]amino]-3-[[(1- methyltetrazol-5-yl)thio]-methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylic acid, which showed comparable potency in vitro and in vivo to that of cefazolin, and, in addition, was more potent than cefazolin against Enterobacter sp. and Providencia stuartii.

Azacycloalkanes: XXXIX. New Syntheses of 1H-Pyrrole-1-carboxylic acid and 1,2-dihydropyrrolo-[1,2-a]pyrazin-3(4H)-one derivatives

New procedures have been developed for the synthesis of α-(2-formyl-1H-pyrrol-1-yl)-substituted carboxylic acids, α-(2-R-aminomethyl-1H-pyrrol-1-yl)-substituted carboxylic acids, and 1,2-dihydropyrrolo-[1,2-a]pyrazin-3(4H)-ones on the basis of furfurol and α-amino acids.

Improved functionalized resin for chemical synthesis

A support functionalized by an indole or pyrrole aldehyde is useful for the solid phase synthesis of amide type compounds.