67473-56-7

Upstream product

• 67159-08-4 7-methyl-2-phenyl-1H-[1,8]naphthyridin-4-one 
• 64194-18-9 6-methyl-2-phenyl-4H-pyrido<1,2-a>pyrimidin-4-one 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 1824-81-3 2-Amino-6-methylpyridine 

Downstream Products

• 286411-04-9 4-(7-methyl-2-phenyl-[1,8]naphthyridin-4-yl)-piperazine-1-carboxylic acid ethyl ester 
• 91860-18-3 Bis-(2-chloro-ethyl)-(7-methyl-2-phenyl-[1,8]naphthyridin-4-yl)-amine 
• 91860-07-0 2-[(2-Hydroxy-ethyl)-(7-methyl-2-phenyl-[1,8]naphthyridin-4-yl)-amino]-ethanol 

Relevant academic research and scientific papers

Inhibitors of Hepatitis C Virus

Macrocyclic peptides are disclosed having the general formula: wherein R3, R3′, R4, R6, R′, X, Q and W are described. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

Inhibitors of Hepatitis C Virus

Macrocyclic peptides are disclosed having the general formula: wherein R3, R′3, R4, R6, R′, X, Q and W are described. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

Hepatitis C virus inhibitors

Macrocyclic peptides are disclosed having the general formula: wherein R′, R3, R3′, R4, R6, X, Q, and W are described. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

Hepatitis C virus inhibitors

The present disclosure is generally directed to antiviral compounds, and more specifically directed to compounds which inhibit the function of the NS3 protease (also referred to herein as “serine protease”) encoded by Hepatitis C virus (HCV), compositions comprising such compounds, and methods for inhibiting the function of the NS3 protease.

HEPATITIS C VIRUS INHIBITORS

Hepatitis C virus inhibitors are disclosed having the general formula:(I) wherein R1, R2, R3, R', B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds toinhibit HCV are also disclosed.

A novel class of highly potent and selective A1 adenosine antagonists: Structure-affinity profile of a series of 1,8-naphthyridine derivatives

A series of 1,8-naphthyridine derivatives (12-36), bearing a phenyl group in position 2 and various substituents in positions 4 and 7, were synthesized in an attempt to obtain potent, selective antagonists for the A1 adenosine receptor subtype.