67475-10-9Relevant academic research and scientific papers
Enantioselective nucleophilic addition to N-(2-pyridylsulfonyl)imines by use of dynamically induced chirality
Sugimoto, Hideki,Nakamura, Shuichi,Hattori, Masataka,Ozeki, Sachiko,Shibata, Norio,Toru, Takeshi
, p. 8941 - 8944 (2005)
Enantioselective nucleophilic addition of Grignard reagents to N-(2-pyridylsulfonyl)imines in the presence of bis(oxazoline) afforded products with good enantioselectivity. Dynamically induced chiralitxy on the sulfur by coordination of a chiral Lewis aci
Enantioselective C-C bond formation to sulfonylimines through use of the 2-pyridinesulfonyl group as a novel stereocontroller
Nakamura, Shuichi,Nakashima, Hiroki,Sugimoto, Hideki,Sano, Hideaki,Hattori, Masataka,Shibata, Norio,Toru, Takeshi
supporting information; experimental part, p. 2145 - 2152 (2009/04/08)
Enantioselective C-C bond formation to 2-pyridinesulfonylimines afforded products with good enantioselectivity. Dynamic induction of chirality on the sulfur by coordination of a chiral Lewis acid to the pyridine nitrogen and one of the prochiral sulfonyl oxygens induces enantioselectivity. Since the 2-pyridine-sulfonyl group can easily be removed after the reaction, it acts not only as an activating group but also as an efficient Stereocontroller.
