674776-35-3

Upstream product

• 169221-13-0 (R)-3-hydroxy-4,4-dimethyl-1-phenylpyrrolidin-2-one 
• 674776-32-0 (+/-)-3-cyano-2-(4-isobutylphenyl)propionyl chloride 
• 674776-29-5 (+/-)-3-cyano-2-(4-isobutylphenyl)propionic acid 
• 674776-27-3 (+/-)-methyl 3-cyano-2-(4-isobutylphenyl)propionate 
• 169221-12-9 (S)-3-hydroxy-4,4-dimethyl-1-phenyl-2-pyrrolidinone 
• 61566-33-4 p-isobutylphenylacetic acid methyl ester 

Downstream Products

• 674776-50-2 (R)-4-Amino-2-(4-isobutyl-phenyl)-butyric acid 
• 674776-34-2 (3R)-4,4-dimethyl-2-oxo-1-phenylpyrrolidin-3-yl (2R)-3-cyano-2-phenylpropionate 
• 169221-13-0 (R)-3-hydroxy-4,4-dimethyl-1-phenylpyrrolidin-2-one 
• 674776-41-1 (R)-3-cyano-2-(4-isobutylphenyl)propionic acid 

Relevant academic research and scientific papers

Stereoselective synthesis of both enantiomers of N-Boc-α-aryl- γ-aminobutyric acids

Esterification of racemic α-aryl-β-cyanopropionic acid chlorides with either (R)- or (S)-N-phenylpantolactam as the chiral auxiliary in the presence of Et3N resulted in the predominant formation of (αR,3′R)- or (αS,3′S)-configured pantolactam c