674801-20-8Relevant academic research and scientific papers
Regioselective acylation of carbohydrate derivatives using lipases leading to a facile two-step procedure for the separation of some α- and β-glucopyranosides and galactopyranosides
Gon?alves, Pedro M.L.,Roberts, Stanley M.,Wan, Peter W.H.
, p. 927 - 932 (2004)
The resolution of α- and β-anomers of glucopyranosides and galactopyranosides was achieved via enzyme-catalysed regioselective acylation. This two-step procedure to prepare pure α- and β-anomers of glycopyranosides would be most useful for the cases where glycosidases are not available or expensive to purchase. From a synthetic viewpoint, the regioselective acylation of glycopyranosides provides access to mono- and di-esters with well-defined substitution patterns.
