674815-02-2Relevant academic research and scientific papers
Synthesis and SAR of selective muscarinic acetylcholine receptor subtype 1 (M1 mAChR) antagonists
Michelle Lewis,Sheffler, Douglas,Williams, Richard,Bridges, Thomas M.,Kennedy, J. Phillip,Brogan,Mulder, Matthew J.,Williams, Lyndsey,Nalywajko, Natalia T.,Niswender, Colleen M.,Weaver, Charles D.,Conn, P. Jeffrey,Lindsley, Craig W.
, p. 885 - 890 (2008/09/19)
This Letter describes the synthesis and SAR, developed through an iterative analogue library approach, of a novel series of selective M1 mAChR antagonists for the potential treatment of Parkinson's disease, dystonia and other movement disorders. Compounds
