675106-36-2Relevant academic research and scientific papers
Tetrahydropyrrolo[3,2-c]azepin-4-ones as a new class of cytotoxic compounds
Martínez, Roberto,ávila, J. Gustavo,Ramírez, Ma. Teresa,Pérez, Araceli,Martínez, ángeles
, p. 4007 - 4016 (2007/10/03)
Pyrroloazepinones 8a-j and 9a-j were designed by structural modification of lead compound 3. These compounds were tested on five tumor cell lines to determine the role of the azeto ring and the 2-methyl substituent in the cytotoxicity of compound 3. Our r
An efficient synthesis of 6,6-dimethyl-2-(4-nitrophenyl)-1-(r-phenyl)-4,5,6,7-tetrahydro-1H-4-indolones using a solid sulfated zirconia as catalyst
Negrón, Guillermo,ángeles, Deyanira,Lomas, Leticia,Martínez, ángeles,Ramírez, Manuel,Martínez, Roberto
, p. 367 - 371 (2007/10/03)
Sulfated zirconium has been found to be an excellent substitute for conventional acids in the tetrahydroindolone derivatives synthesis, resulting in milder reaction conditions, bringing down reaction temperature and formulating more efficient isolation and purification procedure.
