675124-49-9

Upstream product

• 145416-96-2 1,3,5-tri-O-benzoyl-2-deoxy-D-ribofuranose 
• 7677-24-9 trimethylsilyl cyanide 
• 452-51-7 D-2-deoxyribose 
• 108647-88-7 ((2R,3S)-3-(benzoyloxy)-5-methoxytetrahydrofuran-2-yl)methyl benzoate 

Downstream Products

• 675124-60-4 3S-benzoyloxy-2R-benzoyloxymethyl-5R/S-[6H-(1,3,4)-thiadiazin-2-amino-5-yl]-tetrahydrofuran 
• 675124-53-5 2-chloro-1-(4S-benzoyloxy-5R-benzoyloxymethyl-tetrahydrofuran-2R/S-yl)-ethanone 
• 675124-52-4 4S-benzoyloxy-5R-benzoyloxymethyl-tetrahydrofuran-2R/S-carbonyl chloride 
• 675124-51-3 2,5-anhydro-4,6-di-O-benzoyl-3-deoxy-D-arabino- and D-ribo-hexonic acid 

Relevant academic research and scientific papers

A parallel synthesis approach towards a family of C-nucleosides

A synthetic route was devised for a sugar based α-chloroketone, which was subsequently used to generate a family of C-nucleosides via parallel synthetic methodology.

Synthesis of C-Nucleosides via Radical Coupling Reaction

Photolysis of O-acyl derivatives of N-hydroxy-2-thiopyridone, prepared from tetrahydrofuran-2-carboxylic acid, D-ribofuranosylmethanoic acid, and D-ribopyranosylmethanoic acid, gave the corresponding C-nucleoside derivatives in the presence of heteroaromatic compounds via radical pathways.The essential step in this method is a radical coupling reaction of D-ribofuranosyl radical or D-ribopyranosyl radical and some heteroaromatic bases.This is a new method for the preparation of C-nucleosides using sugar carboxylic acids.