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1-Palmitoyl-2-oleoylphosphatidylcholine (POPC) is a type of phospholipid, which is a major component of cell membranes. It consists of a glycerol backbone, two fatty acid chains (one palmitoyl and one oleoyl), a phosphate group, and a choline head group. POPC plays a crucial role in maintaining the structural integrity and fluidity of cell membranes, as well as participating in various cellular processes such as signal transduction and membrane fusion. Due to its amphiphilic nature, it can form bilayers in an aqueous environment, mimicking the natural cell membrane structure. This property makes POPC a valuable compound for studying membrane-related phenomena and for use in the development of drug delivery systems and artificial cell models.

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  • 6753-55-5 Structure
  • Basic information

    1. Product Name: 1-palmitoyl-2-oleoylphosphatidylcholine
    2. Synonyms: ethanaminium, 2-[[hydroxy[3-[(1-oxohexadecyl)oxy]-2-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propoxy]phosphinyl]oxy]-N,N,N-trimethyl-, inner salt
    3. CAS NO:6753-55-5
    4. Molecular Formula: C42H82NO8P
    5. Molecular Weight: 760.076141
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 6753-55-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: °Cat760mmHg
    3. Flash Point: °C
    4. Appearance: /
    5. Density: g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-palmitoyl-2-oleoylphosphatidylcholine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-palmitoyl-2-oleoylphosphatidylcholine(6753-55-5)
    11. EPA Substance Registry System: 1-palmitoyl-2-oleoylphosphatidylcholine(6753-55-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 6753-55-5(Hazardous Substances Data)

6753-55-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6753-55-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,5 and 3 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6753-55:
(6*6)+(5*7)+(4*5)+(3*3)+(2*5)+(1*5)=115
115 % 10 = 5
So 6753-55-5 is a valid CAS Registry Number.
InChI:InChI=1/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-

6753-55-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine

1.2 Other means of identification

Product number -
Other names [3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6753-55-5 SDS

6753-55-5Relevant articles and documents

Treatment of age-related memory impairment

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Page/Page column 7-8, (2008/06/13)

Symptoms, including biochemical correlates, of age-related memory loss (ARML) in a mammal are beneficially affected by administering to the mammal small doses of bodies, such as liposomes, of a size resembling that of mammalian cells, the bodies having phosphate glycerol head groups presented exteriorly on their surfaces. Preferred are liposomes comprised of 50-100% phosphatidylglycerol, with the phosphoglycerol headgroups thereof exteriorly presented.

Synthesis of Benzophenone-Containing Analogues of Phosphatidylcholine

Wang, Pingzhen,Blank, David H.,Spencer, Thomas A.

, p. 2693 - 2702 (2007/10/03)

As part of a collaborative study of cellular efflux of cholesterol and phospholipids, photoactivable analogues 4-8 of phosphatidylcholine (PC) having benzophenone groups in the choline moiety and at the end of the C2 and C1 alkyl chains have been synthesized. The efficient preparation via Suzuki coupling of the appropriate long-chain benzophenone-containing carboxylic acid and alcohol and their incorporation by adaptation of known approaches into the acyl- and ether-linked PC analogues 6-8 are described. Development of a method for radiolabeling these PC analogues, via hydrogenation of a double bond in modified side chains, is also described.

Synthesis of a small library of mixed-acid phospholipids from D-mannitol as a homochiral starting material

Xia, Jie,Hui, Yong-Zheng

, p. 1659 - 1663 (2007/10/03)

Synthesis of a series of mixed-acid phospholipids containing a polyunsaturated fatty acid using a newly protecting strategy are described. Thus, benzyl and methyl α-(2,4-dinitrophenyl)acetic acid which were respectively removed by BCl3 and 354 nm light are used as protecting groups.

Method of lowering the viscosity of mucus

-

, (2008/06/13)

The use of phospholipids of the following formula to reduce the viscosity of mucus in a patient is described: STR1 wherein one of X, Y, or Z represent: STR2 in which each R represents hydrogen or methyl, and each of the other two of X, Y, or Z represents --CO--R1 in which R1 represents linear or branched C11-21 alkyl or C11-21 alkenyl, unsubstituted or substituted with one or more substituents selected from the group consisting of halo, C1-6 linear or branched alkoxy or cyano.

Liposome-Mediated Enzymatic Synthesis of Phosphatidylcholine as an Approach to Self-Replicating Liposomes

Schmidli, Peter Kurt,Schurtenberger, Peter,Luisi, Pier Luigi

, p. 8127 - 8130 (2007/10/02)

The four enzymes of the salvage pathway for phosphatidylcholine synthesis sn-glycerol-3-phosphate acyltransferase, 1-acyl-sn-glycerol-3-phosphate acyltransferase, phosphatidate phosphatase, and cytidinediphosphocholine phosphocholinetransferase were simul

Single-stage process for preparing mixed-substituted 1,2-diacyl-sn-clycero-3-phosphocholines

-

, (2008/06/13)

Single-stage process for preparing mixed-substituted enantiomerically pure 1,2-diacyl-sn-glycero-3-phosphocholines of general formula I STR1 in which R1 and R2 are different and independently of each other denote a substituted or uns

Derivatives of glycerophosphocholine and glycerophosphoethanolamine, their preparation and their use

-

, (2008/06/13)

The invention relates to new triphenylmethyl derivatives of sn-glycero-3-phosphocholine and sn-glycero-3-phosphoethanolamine of the general formula STR1 in which T denotes a triphenylmethyl group which is unsubstituted or monosubstituted or polysubstitute

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