675571-69-4

Upstream product

• 13128-74-0 4,4-diphenylcyclohexane-1,3-dione 
• 4528-64-7 4,4-diphenyl-2-cyclohexen-1-one 
• 781-35-1 1,1-diphenylacetone 

Relevant academic research and scientific papers

Expedient enantiospecific synthesis of RP 73613: A new selective non-peptide NK1 antagonist

The synthesis of RP 73613 was achieved in 13 steps with an overall yield of 12%. The strategy was based on a [3 + 2] azomethine ylid dipolar cycloaddition to generate the bicyclic framework and the asymmetric was introduced by resolution.

Isoindolone derivatives

New isoindolone derivatives of general formula (I) are STR1 disclosed in which the radicals R represent hydrogen atoms or, together, form a bond, the symbol R' represents a hydrogen atom or a readily removable radical and the symbols R" are identical and