675571-69-4Relevant academic research and scientific papers
Expedient enantiospecific synthesis of RP 73613: A new selective non-peptide NK1 antagonist
Daubie, Christophe,Mutti, Stephane
, p. 7743 - 7744 (2007/10/03)
The synthesis of RP 73613 was achieved in 13 steps with an overall yield of 12%. The strategy was based on a [3 + 2] azomethine ylid dipolar cycloaddition to generate the bicyclic framework and the asymmetric was introduced by resolution.
Isoindolone derivatives
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, (2008/06/13)
New isoindolone derivatives of general formula (I) are STR1 disclosed in which the radicals R represent hydrogen atoms or, together, form a bond, the symbol R' represents a hydrogen atom or a readily removable radical and the symbols R" are identical and
