13128-74-0Relevant academic research and scientific papers
Synthesis of 1,3-Cycloalkadienes from Cycloalkenes: Unprecedented Reactivity of Oxoammonium Salts
Nagasawa, Shota,Sasano, Yusuke,Iwabuchi, Yoshiharu
supporting information, p. 13189 - 13194 (2016/10/30)
Few methods allow for the direct conversion of cycloalkenes into cycloalkadienes with high chemo- and regioselectivity. Herein, we report a convenient one-pot process for this transformation that involves the unprecedented N-preferential group transfer of N-oxoammonium salts to cycloalkenes, followed by Cope elimination, to afford cycloalkadienes at room temperature and pressure.
Dioxocyclohexane carboxylic acid phenyl amide derivatives for modulating voltage-gated potassium channels and pharmaceutical compositions containing the same
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Page/Page column 15, (2010/02/15)
Dioxocyclohexane carboxylic acid phenyl amide derivatives of Formula (I) or a tautomer or a pharmaceutically acceptable salt thereof or both, and pharmaceutical compositions containing the same are provided: [image] The dioxocyclohexane carboxylic acid phenyl amide derivatives are useful for treating a variety of conditions associated with the abnormal modulation of one or more Kv1.1 voltage-gated potassium channels.
Expedient enantiospecific synthesis of RP 73613: A new selective non-peptide NK1 antagonist
Daubie, Christophe,Mutti, Stephane
, p. 7743 - 7744 (2007/10/03)
The synthesis of RP 73613 was achieved in 13 steps with an overall yield of 12%. The strategy was based on a [3 + 2] azomethine ylid dipolar cycloaddition to generate the bicyclic framework and the asymmetric was introduced by resolution.
Type A Zwitterions and Cyclohexadienone Photochemical Rearrangements. Mechanistic and Exploratory Organic Photochemistry
Zimmerman, Howard E.,Pasteris, Robert J.
, p. 4876 - 4891 (2007/10/02)
The photochemistry of 3-methoxy-4,4-diphenyl-2,5-cyclohexadienone was studied.The type A rearrangement proved to be regioselective with a preference for formation of 4-methoxy-6,6-diphenylbicyclohex-3-en-2-one relative to 5-methoxy-6,6-diphenylbicy
