67562-76-9Relevant academic research and scientific papers
O-aryl ethers of morphinans
-
, (2008/06/13)
The use of a compound of the formula: wherein R2 is aryl, heteroaryl or a group of the formula R20 and R1 is hydrogen, alkyl, a group of the formula -C(Y,Y1)CH2OH or -CH2W, wherein one of Y and Y1 is hydrogen and the other
Potential synthetic codeine substitutes: (-)-3-O-aryl-N-methylmorphinans
Mohacsi,Hayes,Spinwall
, p. 1219 - 1222 (2007/10/02)
A series of novel O-aryl-N-methylmorphinans were synthesized by the Ullmann reaction from levorphanol in our search for a synthetic codeine substitute with reduced addition liability. The compounds were evaluated for antinociceptive potency and receptor b
Process for preparing 3-phenoxy morphinans
-
, (2008/06/13)
The preparation of 3-phenoxy N-substituted morphinans, useful as analgesics from 1-(p-hydroxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline or cyclohexen-(1)-yl-ethylamine and p-phenoxyphenylacetic acid is described.
3-Phenoxymorphinans and derivatives thereof
-
, (2008/06/13)
Levo-rotary 3-phenoxy N-substituted morphinans and derivatives thereof useful as analgesics and/or narcotic antagonists and their preparation form (-)-3-hydroxy-N-lower alkyl morphinan including intermediates in this preparation.
3-Phenoxymorphinans and derivatives thereof
-
, (2008/06/13)
Levo-rotary 3-phenoxy N-substituted morphinans and derivatives thereof useful as analgesics and/or narcotic antagonists and their preparation form (-)-3-hydroxy-N-lower alkyl morphinan including intermediates in this preparation.
