6758-34-5 Usage
Uses
Used in Pharmaceutical Industry:
2-(Hydroxymethyl)-5-trifluoromethyl-1H-benzimidazole is used as a pharmaceutical compound for its antioxidant, antimicrobial, and antifungal properties. Its diverse range of biological activities makes it a promising candidate for the development of new drugs to combat various diseases and infections.
Used in Antimicrobial Applications:
In the field of antimicrobial research, 2-(Hydroxymethyl)-5-trifluoromethyl-1H-benzimidazole is used as an antimicrobial agent to target and inhibit the growth of harmful microorganisms, such as bacteria and fungi. Its ability to disrupt microbial processes and protect against infections highlights its potential as a therapeutic agent in treating various infectious diseases.
Used in Antifungal Applications:
2-(Hydroxymethyl)-5-trifluoromethyl-1H-benzimidazole is used as an antifungal agent to combat fungal infections. Its effectiveness in inhibiting fungal growth and preventing the spread of fungal diseases makes it a valuable asset in the development of new antifungal medications.
Used in Neurodegenerative Disease Treatment:
In the area of neurodegenerative disease research, 2-(Hydroxymethyl)-5-trifluoromethyl-1H-benzimidazole is being investigated for its potential use in the treatment of neurodegenerative diseases. Its ability to modulate enzyme activities and protein production suggests that it may have therapeutic benefits in managing the progression of these debilitating conditions.
Used in Drug Development Research:
2-(Hydroxymethyl)-5-trifluoromethyl-1H-benzimidazole is used in drug development research to explore its pharmacological potential and identify any potential side effects or toxicities. Further studies are necessary to fully understand its therapeutic applications and ensure its safety and efficacy as a pharmaceutical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 6758-34-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,5 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6758-34:
(6*6)+(5*7)+(4*5)+(3*8)+(2*3)+(1*4)=125
125 % 10 = 5
So 6758-34-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H7F3N2O/c10-9(11,12)5-1-2-6-7(3-5)14-8(4-15)13-6/h1-3,15H,4H2,(H,13,14)
6758-34-5Relevant academic research and scientific papers
Sustainable Synthesis of 2-Hydroxymethylbenzimidazoles using D-Fructose as a C2 Synthon
Raja, Dineshkumar,Philips, Abigail,Sundaramurthy, Devikala,Chandru Senadi, Gopal
supporting information, p. 3754 - 3759 (2021/10/14)
D-fructose, a biomass-derived carbohydrate has been identified as an environmentally benign C2 synthon in the preparation of synthetically useful 2-hydroxymethylbenzimidazole derivatives by coupling with 1,2-phenylenediamines. Proof of concept was established by synthesizing 23 examples using BF3.OEt2 (20 mol%), TBHP (5.5 M, decane) (1.0 equiv.) in CH3CN at 90 °C for 1 h. The pivotal features of this method include metal-free conditions, short time, good functional group tolerance, gram scale feasibility and the synthesis of benzimidazole fused 1,4-oxazine. Control studies with conventional C2 synthons did not produce the desired product, thus suggesting a new reaction pathway from D-fructose.
