6760-40-3

Usage

Uses

Used in Pharmaceutical Industry:
1,2-DiMethylquinolin-4(1H)-one is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Organic Synthesis:
In the field of organic synthesis, 1,2-DiMethylquinolin-4(1H)-one serves as a versatile building block. It can be utilized to create a range of complex organic molecules, contributing to the advancement of chemical research and the development of novel materials.
Used in Materials Science:
1,2-DiMethylquinolin-4(1H)-one's potential applications extend to materials science, where it may be employed in the design and synthesis of new materials with specific properties. Its incorporation into these materials could lead to innovations in areas such as electronics, coatings, or advanced materials for various industries.
Used in Agrochemicals:
1,2-DiMethylquinolin-4(1H)-one may also find use in the agrochemical industry, where it could be utilized in the development of new pesticides, herbicides, or other agricultural chemicals. Its unique structure may provide advantages in terms of selectivity, efficacy, or environmental impact compared to existing products.
Further research and exploration of 1,2-DiMethylquinolin-4(1H)-one are necessary to fully understand its potential applications and to unlock its full potential across various fields.

InChI:InChI=1/C11H11NO/c1-8-7-11(13)9-5-3-4-6-10(9)12(8)2/h3-7H,1-2H3

Upstream product

• 91420-11-0 1,2-dimethylquinolinium chloride 
• 92028-49-4 4-(allyloxy)-2-methylquinoline 
• 10328-92-4 N-Methylisatoic anhydride 
• 67-64-1 acetone 
• 83-54-5 1-methyl-4-quinolone 
• 917-54-4 methyllithium 
• 31835-53-7 4-methoxy-2-methyl-quinoline 

Relevant academic research and scientific papers

Utilization of aromatic denitrocyclization reaction for the synthesis of 3-unsubstituted 1,4-dihydroquinolin-4-one derivatives

Synthesis of 3-unsubstituted 1-alkyl- and 1-aryl-1,4-dihydroquinolin-4-ones from 2-nitroacetophenone via the corresponding 3-amino-1-(2-nitrophenyl)prop-2- en-1-ones and -but-2-en-1-ones by denitrocyclization reaction is described. The nucleophilic cyclization was achieved either by sodium hydride or potassium carbonate in DMF.

Reactions of 1-Methyl-4-quinolone with 2-Lithio-1,3-dithianes

Nucleophiles, including lithiated 1,3-dithianes, add to 1-methyl-4-quinolone at the 2-position; in some cases initial adducts were subsequently trapped with added electrophile.

The Chemistry of 2H-3,1-Benzoxazine-2,4(1H)-dione (Isatoic Anhydride). 17. Synthesis of 2-Alkyl-4-quinolone Alkaloids via a One-step Reaction of N-Methylisatoic Anhydride with Methyl Ketone Enolates

Lithium enolates derived from aliphatic methyl ketones react with N-methylisatoic anhydride (5) at -78 deg C to give 2-alkyl-4-quinolone alkaloids 7 in a single step.The method was used to synthesize both double bond isomers of 1-methyl-2-(8-tridecenyl)-4(1H)-quinolinone (8) thereby showing that the alkaloid evocarpine possesses the Z-olefin stereochemistry 8a.Reduction of 8a provided the alkaloid dihydroevocarpine (16).Compound 16 was also directly prepared from the reaction of 5 with the lithium enolate of 2-pentadecanone.

The Oxidation of 1-Alkyl(aryl)quinolinium Chlorides with Rabbit Liver Aldehyde Oxidase

1-Alkyl(aryl)quinolinium chlorides are oxidized by rabbit liver aldehyde oxidase at positions C-2 and C-4.The site and the maximum rate of oxidation are dependent on the size and the steric conformation of the N-1 substituent.The presence of a 3-carboxamido group directs the oxidation completely to position C-4, irrespective of the size of the N-substituent.Application of covalent amination in liquid ammonia as an "enzyme model" for the oxidation of these compounds shows little resemblance.