676134-94-4

Basic information

• Product Name: Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-2-hydroxy-3-[[1-[3-(1-methylethyl )phenyl]cyclohexyl]amino]propyl]-, 1,1-dimethylethyl ester
• CAS NO: 676134-94-4
• Molecular Formula: C30H42F2N2O3
• Molecular Weight: 516.672
• Mol File: 676134-94-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-2-hydroxy-3-[[1-[3-(1-methylethyl )phenyl]cyclohexyl]amino]propyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-2-hydroxy-3-[[1-[3-(1-methylethyl )phenyl]cyclohexyl]amino]propyl]-, 1,1-dimethylethyl ester(676134-94-4)
• EPA Substance Registry System: Carbamic acid, [(1S,2R)-1-[(3,5-difluorophenyl)methyl]-2-hydroxy-3-[[1-[3-(1-methylethyl )phenyl]cyclohexyl]amino]propyl]-, 1,1-dimethylethyl ester(676134-94-4)

Safety Data

• Hazardous Substances Data: 676134-94-4(Hazardous Substances Data)

Upstream product

• 388071-27-0 tert-butyl (1S)-2-(3,5-difluorophenyl)-1-[(2S)-oxiranyl]ethylcarbamate 
• 676134-90-0 1-(3-isopropylphenyl)cyclohexanamine hydrochloride 
• 676134-99-9 1-(3-isopropylphenyl)cyclohexanamine 

Downstream Products

• 676134-96-6 (2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-{[1-(3-isopropylphenyl)cyclohexyl]amino}butan-2-ol 

Relevant articles and documents

SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS

The invention relates to acetyl 2-hydroxy-1,3-diaminospirocyclohexanes and derivatives thereof that are useful in treating at least one disease, disorder, and condition associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and condition associated with abnormal deposition of A-beta protein.

METHODS OF TREATMENT OF AMYLOIDOSIS USING ASPARTYL-PROTEASE INHIBITORS

The invention relates to acetyl 2-hydroxy-1,3-diaminospirocyclohexanes and derivatives thereof that are useful in treating diseases, disorders, and conditions associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.