676154-04-4

Upstream product

• 676153-96-1 (2R,3S)-3-Benzyloxy-2-benzyloxymethyl-5-methyl-2,3-dihydro-pyran-4-one 
• 74-88-4 methyl iodide 
• 80040-79-5 3,4,6-tri-O-benzyl-D-galactal 
• 100-44-7 benzyl chloride 
• 149561-64-8 (-)-(2R,3S)-3-(Benzyloxy)-2-<(benzyloxy)methyl>-2,3-dihydro-4H-pyran-4-one 
• 4098-06-0 triacetyl-D-galactal 
• 676153-95-0 3-benzyloxy-2-benzyloxymethyl-5-iodo-2,3-dihydropyran-4-one 

Downstream Products

• 676154-06-6 2-[2-((2R,4R,5R,6R)-5-Benzyloxy-6-benzyloxymethyl-4-methoxy-3,3-dimethyl-tetrahydro-pyran-2-yl)-ethyl]-[1,3]dioxane 
• 676154-05-5 (2R,4R,5R,6R)-5-Benzyloxy-6-benzyloxymethyl-2-(2-[1,3]dioxan-2-yl-ethyl)-3,3-dimethyl-tetrahydro-pyran-4-ol 

Relevant academic research and scientific papers

Synthesis of model ring systems related to C10-C18 analogues of the mycalamides/theopederins

Conjugate addition to D-galactose-derived pyranones 8 and 10, with in situ enolate alkylation, or protonation, provides pyranones 11-13 or 16-19. These are related to the C10-C18 fragment of the mycalamides and provide a short entry to C10, C11, C14 and C