67618-11-5Relevant academic research and scientific papers
High-throughput screen for inhibitors of protein-protein interactions in a reconstituted heat shock protein 70 (Hsp70) complex
Taylor, Isabelle R.,Dunyak, Bryan M.,Komiyama, Tomoko,Shao, Hao,Ran, Xu,Assimon, Victoria A.,Kalyanaraman, Chakrapani,Rauch, Jennifer N.,Jacobson, Matthew P.,Zuiderweg, Erik R.P.,Gestwicki, Jason E.
, p. 4014 - 4025 (2018/03/25)
Protein-protein interactions (PPIs) are an important category of putative drug targets. Improvements in high-throughput screening (HTS) have significantly accelerated the discovery of inhibitors for some categories of PPIs. However, methods suitable for s
Improved Procedures for the Preparation of Cycloalkyl-, Arylalkyl-, and Arylthioureas
Rasmussen, C. R.,Villani, F. J.,Weaner, L. E.,Reynolds, B. E.,Hood, A. R.,et al.
, p. 456 - 459 (2007/10/02)
An improved procedure for the preparation of arylthioureas consists of the reaction of benzoyl isothiocyanate with anilines in acetone and debenzoylation of the resultant N-aryl-N'-benzoylthioureas with 5percent aqueous sodium hydroxide.Bicycloalkylthioureas and N-(arylalkyl)thioureas (e.g. 9H-9-fluorenylthiourea) are directly prepared from the corresponding isothiocyanates and ammonia.
Heterocyclic derivatives of guanidine
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, (2008/06/13)
5-Membered, 6-membered and 7-membered heterocyclic derivatives of guanidine having hypoglycemic activity.
