67620-24-0

Basic information

• Product Name: N-[10-(ethylamino)-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
• Synonyms: acetamide, N-[(10Z)-10-(ethylimino)-5,6,7,10-tetrahydro-9-hydroxy-1,2,3-trimethoxybenzo[a]heptalen-7-yl]-; acetamide, N-[10-(ethylamino)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-9-oxobenzo[a]heptalen-7-yl]-; N-[(10Z)-10-(ethylimino)-9-hydroxy-1,2,3-trimethoxy-5,6,7,10-tetrahydrobenzo[a]heptalen-7-yl]acetamide; N-[10-(Ethylamino)-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide
• CAS NO: 67620-24-0
• Molecular Formula: C₂₃H₂₈N₂O₅
• Molecular Weight: 412.4788
• Mol File: 67620-24-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 727°C at 760 mmHg
• Flash Point: 393.5°C
• Density: 1.22g/cm³
• Vapor Pressure: 5.43E-21mmHg at 25°C
• Refractive Index: 1.589
• CAS DataBase Reference: N-[10-(ethylamino)-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[10-(ethylamino)-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide(67620-24-0)
• EPA Substance Registry System: N-[10-(ethylamino)-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide(67620-24-0)

Safety Data

• Hazardous Substances Data: 67620-24-0(Hazardous Substances Data)

Upstream product

• 64-86-8 colchicine 
• 75-04-7 ethylamine 

Relevant articles and documents

Antitumor agents. Part 186: Synthesis and biological evaluation of demethylcolchiceinamide analogues as cytotoxic DNA topoisomerase II inhibitors

Demethylation of colchiceinamide (2) and its analogues (3-10) afforded a novel class of mammalian DNA topoisomerase II inhibitors (2a-10a) without displaying tubulin inhibitory activity. All target compounds inhibited the catalytic activity of topoisomera