676227-82-0Relevant academic research and scientific papers
Efficient synthesis of core 2 class glycosyl amino acids by one-pot glycosylation approach
Tanaka, Hiroshi,Adachi, Masaatsu,Takahashi, Takashi
, p. 1433 - 1436 (2007/10/03)
We describe the one-pot synthesis of core 2 class branched oligosaccharides initiated by chemo-selective glycosylation of silyl ether. Glycosylation of 6-O-silyl-4-benzyl-2-azido-thiogalactoside with glycosyl fluoride provided selectively 6-glycosylated thioglycoside without both O-glycosylation at the 3 position and S-glycosylation. Subsequent coupling of galactosyl fluoride and amino acids afforded the protected branched oligosaccharides in good yields.
