676273-41-9Relevant academic research and scientific papers
Conformationally restricted homotryptamines. Part 5: 3-(trans-2-aminomethylcyclopentyl)indoles as potent selective serotonin reuptake inhibitors
Denhart, Derek J.,Deskus, Jeffrey A.,Ditta, Jonathan L.,Gao, Qi,Dalton King,Kozlowski, Edward S.,Meng, Zhaoxing,LaPaglia, Melissa A.,Mattson, Gail K.,Molski, Thaddeus F.,Taber, Matthew T.,Lodge, Nicholas J.,Mattson, Ronald J.,Macor, John E.
, p. 4031 - 4033 (2009)
A series of racemic 3-(trans-2-aminomethylcyclopentyl)indoles was synthesized and found to have potent binding to the human serotonin transporter (hSERT). The most active analog was synthesized stereospecifically and the active enantiomer was shown to hav
