676273-39-5

Usage

Uses

Used in Medicinal Chemistry:
3-Iodo-1-tosyl-1H-indole-5-carbonitrile is utilized as a precursor in the synthesis of various biologically active molecules, playing a crucial role in the development of new pharmaceuticals.
Used in Drug Synthesis:
In the pharmaceutical industry, 3-Iodo-1-tosyl-1H-indole-5-carbonitrile is employed as a key intermediate for the creation of potential drug candidates aimed at treating a range of diseases, including cancer and neurological disorders.
Used in Organic Synthesis Research:
3-Iodo-1-tosyl-1H-indole-5-carbonitrile serves as a versatile building block in organic synthesis, facilitating the development of complex molecular structures and contributing to the advancement of chemical science.
3-Iodo-1-tosyl-1h-indole-5-carbonitrile's potential as a drug candidate is attributed to its unique structural features, which allow for targeted interactions with biological targets, thus offering therapeutic benefits in various medical conditions.

Upstream product

• 1092114-59-4 3-iodo-1H-indole-5-carbonitrile 
• 98-59-9 p-toluenesulfonyl chloride 
• 15861-24-2 1H-indole-5-carbonitrile 

Downstream Products

• 1027787-57-0 C₂₄H₁₆N₂O₂S₂ 
• 676273-41-9 2-[5-Cyano-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-cyclopent-1-ene Carboxylic Acid Ethyl Ester 
• 1401349-98-1 N-(3-(3-iodo-1-tosyl-1H-indol-5-yl)-1,2,4-oxadiazol-5-yl)acetamide 
• 1401349-97-0 3-(3-(6-isopropoxypyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-N-isopropyl-1,2,4-oxadiazol-5-amine 
• 1401349-96-9 3-(3-iodo-1-tosyl-1H-indol-5-yl)-N-isopropyl-1,2,4-oxadiazol-5-amine 
• 1401349-95-8 3-(3-(6-isopropoxypyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-N-methyl-1,2,4-oxadiazol-5-amine 
• 1401349-94-7 3-(3-iodo-1-tosyl-1H-indol-5-yl)-N-methyl-1,2,4-oxadiazol-5-amine 
• 1401349-93-6 3-(3-(6-isopropoxypyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-1,2,4-oxadiazol-5-amine 
• 1401349-91-4 3-(3-(6-(isopropylamino)pyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-1,2,4-oxadiazol-5-amine 
• 1401349-90-3 3-(3-(6-isopropoxypyridin-2-yl)-1-tosyl-1H-indol-5-yl)-1,2,4-oxadiazol-5-amine 
• 1401349-89-0 3-(3-iodo-1-tosyl-1H-indol-5-yl)-1,2,4-oxadiazol-5-amine 
• 1401349-88-9 3-(3-iodo-1-tosyl-1H-indol-5-yl)-5-(trichloromethyl)-1,2,4-oxadiazole 
• 1401349-87-8 N'-hydroxy-3-iodo-1-tosyl-1H-indole-5-carboximidamide 
• 676273-40-8 1-(Toluene-4-sulfonyl)-3-tributylstannanyl-1H-indole-5-carbonitrile 

Relevant academic research and scientific papers

H-bonding vs Protonation of Alkynes in Regioselective Hydroamination Reactions: A Glimpse into the Reactivity of Arylogous Ynolethers and Ynamines

In this paper is described the competition and transition between hydrogen bonding and protonation of alkynes connected, on one side, to various aromatic rings and to chiral amino ester appendages on the other side. While the first mode of activation indu

HETEROARYL COMPOUNDS AS AGROCHEMICAL FUNGICIDES

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SYNTHESIS OF A SEROTONIN REUPTAKE INHIBITOR

Process for the preparation of a piperazinyl derivative, and its intermediates, which has known activity as a serotonin reuptake inhibitor and is used in therapy for treating serious symptoms of depression in adults.

Synthesis of a serotonin reuptake inhibitor

Process for the preparation of the piperazinyl derivative vilazodone, having activity as a serotonin reuptake inhibitor and used in therapy for treating serious symptoms of depression in adults, and its synthetic intermediates.

AZOLE COMPOUNDS AS PIM INHIBITORS

The invention relates to bicyclic compounds of formulas I and Ia, and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of Pim-1 and/or Pim-2, and/or Pim-3 protein kinase activity or enzyme function. In still further em

Conformationally restricted homotryptamines. Part 5: 3-(trans-2-aminomethylcyclopentyl)indoles as potent selective serotonin reuptake inhibitors

A series of racemic 3-(trans-2-aminomethylcyclopentyl)indoles was synthesized and found to have potent binding to the human serotonin transporter (hSERT). The most active analog was synthesized stereospecifically and the active enantiomer was shown to hav

Compounds for the treatment of premature ejaculation

The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts or solvates thereof and pharmaceutically acceptable formulations comprising said compounds useful for the treatment of premature ejaculation, depression, atten