67631-95-2Relevant articles and documents
Regioselective Pseudomonas cepacia lipase mediated amidations of benzyl esters with diamines
Adamczyk, Maciej,Grote, Jonathan
, p. 2099 - 2100 (2007/10/03)
Novel Pseudomonas cepacia catalyzed amidations of benzyl esters demonstrate excellent regioselectivity with both symmetrical and unsymmetrical diamines, producing high yields of easily isolated amide products under mild conditions.
Anti-inflammatory 1-phenylethanolamine derivatives pharmaceutical compositions thereof and processes for their manufacture
-
, (2008/06/13)
The invention relates to topically anti-inflammatory 1-phenylethanolamine derivatives of the general formula I: STR1 or acid-addition salts thereof, to pharmaceutical compositions thereof, and to analogy processes for their manufacture. A representative compound is 1-(4-amino-3,5-dichlorophenyl)-2-[1,1-dimethyl-2-(2-phenylacetamido)ethylamino]ethanol. The derivatives are useful in particular for the treatment of inflammatory diseases or conditions of the skin.