676324-78-0Relevant articles and documents
MACROCYCLIC THERAPEUTIC AGENTS, METHODS OF MANUFACTURE, AND METHODS OF TREATMENT
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Page/Page column 65; 66, (2015/09/28)
The instant invention describes macrocyclic compounds having therapeutic activity, and the mechanism and methods of treating disorders such as autoimmune diseases, inflammation, and cancer, tumors and cell proliferation related disorders.
Synthesis of the polyketide segment of apratoxin A
Xu, Zhengshuang,Chen, Zhiyong,Ye, Tao
, p. 355 - 363 (2007/10/03)
Apratoxin A 1 is a potent cytotoxic agent extracted from a marine cyanobacterium. We report the results of our synthetic approaches to the polyketide segment 3-OTBS-7-OPMB-2,5,8,8-tetramethylnonanoic acid 4, and the scope and limitations of these approach