676349-24-9

Upstream product

• 95409-25-9 4-(benzyloxy)but-2-ynal 
• 676349-22-7 ((1Z,3E)-5-Benzyloxy-1-methyl-penta-1,3-dienyloxy)-tert-butyl-dimethyl-silane 
• 676349-21-6 (E)-6-Benzyloxy-hex-4-en-2-one 
• 89358-30-5 benzyl (2E)-4-bromobut-2-en-1-yl ether 
• 4039-82-1 Benzyl propargyl ether 

Downstream Products

• 676349-34-1 (1R,2R,3R)-4-Benzyloxy-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-1-(2-methyl-[1,3]dioxolan-2-yl)-butan-1-ol 

Relevant academic research and scientific papers

Furanose Synthesis via Regioselective Dihydroxylation of 1-Silyloxy-1,3-dienes: Application to the Furanose Unit of 4-epi-Hygromycin A

Asymmetric dihydroxylation of a 1-silyloxy-1,3-diene is shown to occur regioselectively on the non-oxygenated alkene. Second dihydroxylation is complicated by over-oxidation to the dione and epimerisation of reaction products. However, subsequent manipula