95409-25-9

Upstream product

• 91142-50-6 4-benzyloxy-2-butyn-1-ol 
• 50-00-0 formaldehyd 
• 4039-82-1 Benzyl propargyl ether 
• 149125-61-1 methyl 4-(benzyloxy)-2-butynoate 
• 68-12-2 N,N-dimethyl-formamide 
• 100-44-7 benzyl chloride 
• 444816-17-5 (4-benzyloxy-but-2-ynyloxy)-triethyl-silane 
• 444816-18-6 1-(benzyloxy)-4-[(tert-butyldimethylsilyl)oxy]-2-butyne 

Downstream Products

• 95127-88-1 2-Benzyloxymethyl-4,5,6-trimethyl-cyclohexa-1,4-dien-1-carbaldehyd 
• 98438-64-3 4-Benzyloxy-butin-⁽²⁾-al-⁽¹⁾-phenylsemicarbazon 
• 94823-92-4 4,5-Dimethyl-2-benzyloxymethyl-cyclohexa-1,4-dien-1-carbaldehyd 
• 252873-95-3 (R)-4-(3-Benzyloxy-prop-1-ynyl)-oxetan-2-one 
• 80885-30-9 (E)-4-(benzyloxy)-2-buten-1-ol 
• 287724-81-6 3-(R)-methyl-4-(R)-(3-benzyloxy-prop-1-ynyl)oxetan-2-one 
• 1138138-95-0 ethyl (E)-6-(benzyloxy)hex-2-en-4-ynoate 

Relevant academic research and scientific papers

Copper-Catalyzed Asymmetric Silylation of Propargyl Dichlorides: Access to Enantioenriched Functionalized Allenylsilanes

A copper-catalyzed silylation of propargyl dichlorides was developed to access chloro-substituted allenylsilanes under mild reaction conditions. Moreover, enantioenriched chloro-substituted allenylsilanes can be synthesized in moderate to high yields and good enantioselectivities with this protocol.

Gold catalysis in stereoselective natural product synthesis: (+)-linalool oxide, (-)-isocyclocapitelline, and (-)-isochrysotricine

A stereoselective synthesis of the tetrahydrofuran-containing natural products (2S,5R)-(+)-linalool oxide (1), (-)-isocyclocapitelline (2), and (-)-isochrysotricine (3) is reported. Key steps are the copper-mediated SN2′-substitution of proparg

Asymmetric direct aldol reactions of acetoacetals catalyzed by a simple chiral primary amine

(Chemical Equation Presented) An asymmetric direct aldol reaction of acetoacetals is described. Under the catalysis of a simple chiral primary amine, the direct aldol reactions of acetoacetals occur exclusively on the γ-position to give vinylogous-type al

Furanose Synthesis via Regioselective Dihydroxylation of 1-Silyloxy-1,3-dienes: Application to the Furanose Unit of 4-epi-Hygromycin A

Asymmetric dihydroxylation of a 1-silyloxy-1,3-diene is shown to occur regioselectively on the non-oxygenated alkene. Second dihydroxylation is complicated by over-oxidation to the dione and epimerisation of reaction products. However, subsequent manipula

Facile cleavage of triethylsilyl (TES) ethers using o-lodoxybenzoic acid (IBX) without affecting tert-butyldimethylsilyl (TBS) ethers

(matrix presented) In DMSO cleavage of triethylsilyl (TES) ethers by o-iodoxybenzoic acid (IBX) was significantly faster than cleavage of tert-butyldimethylsilyl (TBS) ethers or further oxidation into carbonyl compounds. In most cases, TES protecting groups be removed in good to excellent yields within 1 h, whereas similar TBS protecting groups remained intact under the same conditions. The procedure also could be adapted for direct one-pot conversion of TES ethers into carbonyl compounds.