676463-23-3Relevant academic research and scientific papers
Design, synthesis, and biological evaluation of new diaminoquinazolines as β-catenin/Tcf4 pathway inhibitors
Mao, Yongjun,Lin, Nan,Tian, Wang,Han, Xiaofeng,Han, Xiaobing,Huang, Ziwei,An, Jing
, p. 1346 - 1359 (2012)
More than 50 new diaminoquinazoline derivatives have been synthesized and evaluated in a colon carcinoma cell growth inhibition assay using HCT116 and SW480 cells. Twenty compounds with good cell growth inhibitory activities (50 values 50 values of 1.5-2.5 μM for HCT116 cells with the luciferase reporter assay.
Improved syntheses of 5′- S -(2-Aminoethyl)-6- N -(4-nitrobenzyl)- 5′-thioadenosine (SAENTA), analogues, and fluorescent probe conjugates: Analysis of cell-surface human equilibrative nucleoside transporter 1 (hENT1) levels for prediction of the antitumor
Robins, Morris J.,Peng, Yunshan,Damaraju, Vijaya L.,Mowles, Delores,Barron, Geraldine,Tackaberry, Tracey,Young, James D.,Cass, Carol E.
supporting information; experimental part, p. 6040 - 6053 (2010/11/02)
5′-S-(2-Aminoethyl)-6-N-(4-nitrobenzyl)-5′-thioadenosine (SAENTA), 5′-S-(2-acetamidoethyl)-6-N-[(4-substituted)benzyl]-5′- thioadenosine analogues, 5′-S-[2-(6-aminohexanamido)]ethyl-6-N-(4- nitrobenzyl)-5′-thioadenosine (SAHENTA), and related compounds we
N-4-Substituted-benzyl-N′-tert-butylbenzyl thioureas as vanilloid receptor ligands: Investigation on the role of methanesulfonamido group in antagonistic activity
Park, Hyeung-Geun,Choi, Ji-Yeon,Choi, Sea-Hoon,Park, Mi-Kyung,Lee, Jihye,Suh, Young-Ger,Cho, Hawon,Oh, Uhtaek,Lee, Jiyoun,Kang, Sang-Uk,Lee, Jeewoo,Kim, Hee-Doo,Park, Young-Ho,Jeong, Yeon Su,Choi, Jin Kyu,Jew, Sang-Sup
, p. 787 - 791 (2007/10/03)
A series of N-4-substituted-benzyl-N′-tert-butylbenzyl thioureas were prepared for the study of their agonistic/antagonistic activities to the vanilloid receptor in rat DRG neurons. Their structure-activity relationship reveals that not only the two oxyge
