1356124-95-2

Upstream product

• 1356124-83-8 N-[4-[[(2-chloroquinazolin-4-yl)amino]methyl]phenyl]-4-methylbenzenesulfonamide 
• 74-89-5 methylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 94838-55-8 tert-butyl (4-aminobenzyl)carbamate 
• 926265-11-4 N-(4-aminomethyl-phenyl)-4-methyl-benzenesulfonamide 
• 676463-23-3 tert-butyl N-{4-[4-(methylphenyl)sulfonamido]benzyl}carbamate 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of new diaminoquinazolines as β-catenin/Tcf4 pathway inhibitors

More than 50 new diaminoquinazoline derivatives have been synthesized and evaluated in a colon carcinoma cell growth inhibition assay using HCT116 and SW480 cells. Twenty compounds with good cell growth inhibitory activities (50 values 50 values of 1.5-2.5 μM for HCT116 cells with the luciferase reporter assay.