676530-22-6Relevant academic research and scientific papers
Solid-phase synthesis of cyclic glycopeptides related to mannopeptimycin derivatives
Wang, Ting-Zhong,Wheless, Karen L.,Sutherland, Alan G.,Dushin, Russell G.
, p. 131 - 135 (2007/10/07)
The mannopeptimycins comprise a novel series of glycopeptide antibiotics that display activity against susceptible and resistant forms of gram-positive bacteria. Low isolated yields of these products from fermentation make the synthesis of easily accessible analogs attractive. A simplified hexapeptide is synthesized using a combination of solid-phase and solution-phase techniques.
