676546-91-1Relevant academic research and scientific papers
Furan ring opening - Pyridine ring closure: New route to quinolines under the Bischler-Napieralski reaction conditions
Butin, Alexander V.,Tsiunchik, Fatima A.,Kostyukova, Olga N.,Uchuskin, Maxim G.,Trushkov, Igor V.
, p. 2629 - 2638 (2011/10/04)
A new approach to highly functionalized quinolines is proposed. This approach is based on the electrophilic recyclization of 2-[2-(acylamino)benzyl] furans under the Bischler-Napieralski reaction conditions. Georg Thieme Verlag Stuttgart. New York.
Simple route to 3-(2-indolyl)-1-propanones via a furan recyclization reaction
Butin, Alexander V.,Smirnov, Sergey K.,Stroganova, Tatyana A.,Bender, Wolfgang,Krapivin, Gennady D.
, p. 474 - 491 (2007/10/03)
A simple route to 1-R-3-(2-indolyl)-1-propanones has been elaborated based on recyclization of 2-(2-aminobenzyl)furan derivatives. Being a modification of the Reissert indole synthesis, our approach employs the furan ring as a source of carbonyl function. This approach is general and allows varying of substituents in aromatic ring as well as in 3-position of indole nucleus.
