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Upstream product

• 6282-02-6 N-(hydroxymethyl)benzamide 
• 13734-41-3 t-Boc-L-valine 
• 160349-61-1 N-[(benzyloxy)carbonyl]-O-[tert-butyl(dimethyl)silyl]-D-serine 
• 6081-61-4 N-(benzyloxycarbonyl)-D-serine 
• 45170-31-8 Boc-N-Me-Val-OH 

Relevant academic research and scientific papers

Solution-phase synthesis and biological evaluation of triostin A and its analogues

Triostin A is a biosynthetic precursor of echinomycin which is one of the most potent hypoxia inducible factor 1 (HIF-1) inhibitors. An improved solution-phase synthesis of triostin A on a preparative scale has been achieved in 17.5% total yield in 13 ste

Synthesis and biological activity of new quinoxaline antibiotics of echinomycin analogues

Novel quinoxaline antibiotics having the methylenedithioether bridge as an analogue of echinomycin have been synthesized by insertion of methylene moiety between -S-S- bond. The compound 1a shows remarkable cytotoxicities against human tumor various cell