676612-41-2

Basic information

• Product Name: 1′-benzyl-3′-hydroxy-1′,3′-dihydro-1H,2′H-3,3′-biindol-2′-one
• Synonyms: 1′-benzyl-3′-hydroxy-1′,3′-dihydro-1H,2′H-3,3′-biindol-2′-one
• CAS NO: 676612-41-2
• Molecular Weight: 354.408
• Mol File: 676612-41-2.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 1′-benzyl-3′-hydroxy-1′,3′-dihydro-1H,2′H-3,3′-biindol-2′-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1′-benzyl-3′-hydroxy-1′,3′-dihydro-1H,2′H-3,3′-biindol-2′-one(676612-41-2)
• EPA Substance Registry System: 1′-benzyl-3′-hydroxy-1′,3′-dihydro-1H,2′H-3,3′-biindol-2′-one(676612-41-2)

Safety Data

• Hazardous Substances Data: 676612-41-2(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 91-56-5 indole-2,3-dione 
• 100-39-0 benzyl bromide 
• 1217-89-6 1-benzylisatin 

Downstream Products

• 1360873-05-7 1-benzyl-3-(1H-indol-3-yl)-3-(2-oxo-2-phenylethyl)indolin-2-one 
• 1609975-91-8 (1'S,3S)-diethyl-1-benzyl-1'-(4-nitrophenyl)-2-oxo-1',2'-dihydrospiro[indoline-3,4'-pyrido[3,4-b]indole]-3',3'(9'H)-dicarboxylate 
• 1609976-19-3 (1'S,3R)-diethyl-1-benzyl-1'-(4-nitrophenyl)-2-oxo-1',2'-dihydrospiro[indoline-3,4'-pyrido[3,4-b]indole]-3',3'(9'H)-dicarboxylate 
• 1609976-12-6 (1'S,3S)-diethyl-1-benzyl-1'-(3-nitrophenyl)-2-oxo-1',2'-dihydrospiro[indoline-3,4'-pyrido[3,4-b]indole]-3',3'(9'H)-dicarboxylate 
• 1609976-40-0 (1'S,3R)-diethyl-1-benzyl-1'-(3-nitrophenyl)-2-oxo-1',2'-dihydrospiro[indoline-3,4'-pyrido[3,4-b]indole]-3',3'(9'H)-dicarboxylate 
• 1609976-13-7 (1'S,3S)-diethyl-1-benzyl-1'-(4-cyanophenyl)-2-oxo-1',2'-dihydrospiro[indoline-3,4'-pyrido[3,4-b]indole]-3',3'(9'H)-dicarboxylate 
• 1609976-14-8 (1'S,3S)-diethyl-1-benzyl-1'-(3,4-dichlorophenyl)-2-oxo-1',2'-dihydrospiro[indoline-3,4'-pyrido[3,4-b]indole]-3',3'(9'H)-dicarboxylate 
• 1609976-42-2 (1'S,3R)-diethyl-1-benzyl-1'-(3,4-dichlorophenyl)-2-oxo-1',2'-dihydrospiro[indoline-3,4'-pyrido[3,4-b]indole]-3',3'(9'H)-dicarboxylate 
• 1609976-16-0 (1'S,3S)-diethyl-1-benzyl-1'-(4-chlorophenyl)-2-oxo-1',2'-dihydrospiro[indoline-3,4'-pyrido[3,4-b]indole]-3',3'(9'H)-dicarboxylate 
• 1609976-43-3 (1'S,3R)-diethyl-1-benzyl-1'-(4-chlorophenyl)-2-oxo-1',2'-dihydrospiro[indoline-3,4'-pyrido[3,4-b]indole]-3',3'(9'H)-dicarboxylate 

Relevant articles and documents

Reductive aromatization of oxindoles to 3-substituted indoles

A practical and scalable approach for the synthesis of 3-substituted indoles is delineated via hydride nucleophilic addition to 3-substituted-2-oxindoles. The reaction proceeds through reductive aromatization involving indolinium ion intermediate. A wide range of 3-functionalized indoles have been synthesized. The method is employed for the synthesis of 3,3?-bis-indoles and a dimeric 3-indole derivative. Moreover, this protocol is used to obtain naturally occuring amino acid tryptamine.

3-Hydroxy-3-((3-methyl-4-nitroisoxazol-5-yl)methyl)indolin-2-one as a versatile intermediate for retro-Henry and Friedel-Crafts alkylation reactions in aqueous medium

The first example of a retro-Henry type reaction is reported using 3-hydroxy-3-((3-methyl-4-nitroisoxazol-5-yl)methyl)indolin-2-ones which are prepared via catalyst-free Henry reaction of 3,5-dimethyl-4-nitroisoxazole and isatin. These compounds were used

The first synthesis of cis-N,N′-dialkylisoindigo derivatives from 3-indolyl-2-oxindoles with DDQ

cis-N,N′-Dialkylisoindigo derivatives were synthesized for the first time by the reaction of 3-indolyl-2-oxindoles with DDQ in aqueous 1,4-dioxane. cis-Isoindigo derivatives were completely isomerized to the corresponding trans-isomers by heating the solu