677026-77-6

Basic information

• Product Name: 4-Piperidinecarboxylic acid, 1-(3-fluoro-2-formylphenyl)-
• CAS NO: 677026-77-6
• Molecular Formula: C13H14FNO3
• Molecular Weight: 251.257
• Mol File: 677026-77-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Piperidinecarboxylic acid, 1-(3-fluoro-2-formylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinecarboxylic acid, 1-(3-fluoro-2-formylphenyl)-(677026-77-6)
• EPA Substance Registry System: 4-Piperidinecarboxylic acid, 1-(3-fluoro-2-formylphenyl)-(677026-77-6)

Safety Data

• Hazardous Substances Data: 677026-77-6(Hazardous Substances Data)

Upstream product

• 2971-79-1 isonipecotic acid methyl ester 

Relevant articles and documents

Synthesis and biological evaluation of piperazine-based derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)

Compound 2 was identified by high throughput screening as a novel PAI-1 inhibitor. Systematic optimization of the A, B, and C segments of 2 resulted in the identification of a more potent compound 39 with good oral bioavailability. The synthesis and SAR d