677026-90-3

Upstream product

• 677026-91-4 methyl 5-[(2R)-2-({(2R)-2-{[tert-butyl(dimethyl)silyl]oxy}-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl}amino)propyl]-1H-indole-2-carboxylate 

Downstream Products

• 757963-72-7 5-[(2R)-2-({(2R)-2-{[tert-butyl(dimethyl)silyl]oxy}-2-[4-hydroxy-3-(hydroxy methyl)phenyl]ethyl}amino)propyl]-N-[cyclobutylmethyl]-1H-indole-2-carboxamide 
• 757963-27-2 5-[(2R)-2-({(2R)-2-Hydroxy-2-(4-hydroxy-3-hydroxymethyl phenyl)ethyl} amino)propyl]-N-(2-trifluoromethoxybenzyl)-1H-indole-2-carboxamide 
• 757963-56-7 5-[(2R)-2-({(2R)-2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)ethyl} amino)propyl]-N-(4-methylsulfamoylbenzyl)-1H-indole-2-carboxamide 
• 677026-85-6 5-[(2R)-2-({(2R)-2-{[tert-butyl(dimethyl)silyl]oxy}-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl}amino)propyl]-N-(2-methoxybenzyl)-1H-indole-2-carboxamide 

Relevant academic research and scientific papers

Indole derivatives as beta-2 agonists

The invention relates to indole derivatives of formula (1) in which R1, R2, R3, R4, R5, R6, R7, R8 and n have the meanings given in claim 1, and to processes for the p

Indole-2-carboxamide derivatives useful as beta-2 agonists

The invention relates to indole derivatives of general formula: and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The indole derivatives according to the present invention are useful in numerous diseases, disorders and conditions. In particular inflammatory, allergic and respiratory diseases, disorders and conditions.